Stony Brook Surgery Blog

  • Update on Innovative Minimally Invasive Techniques for Thyroid, Head and Neck Cancers

    Innovative Minimally Invasive Techniques for Thyroid, Head and Neck Cancers


    Click on image for enlarged and printable program announcement.

         

    Come to our community update on head and neck cancers, and learn about the latest treatment advances in minimally invasive surgery and reconstructive surgery.

    • When — Wednesday, May 23, from 7 to 8:30 pm
    • Where — Stony Brook Cancer Center (map/directions)

    Radiation oncology treatment, speech pathology, and the latest research will also be discussed. A question-and-answer session will follow the presentation. Speakers are:

    Ghassan J. Samara, MD, Director, Head and Neck, Thyroid Cancer Team, and Director, Rhinology/Research

    Mark F. Marzouk, MD, Department of Surgery, Division of Otolaryngology-Head and Neck Surgery

    Roger Keresztes, MD, Department of Medicine, Division of Hematology and Oncology

    Tamara Weiss, MD, MS, Department of Radiation Oncology

    Community members, patients, family members, caregivers, and healthcare professionals are welcome. Light refreshments will be served.

    Click here for details.

  • Texas Man Travels to Stony Brook for Minimally Invasive Salivary Gland Treatment

    Patient Flies Back Home the Same Day His Problem Is Diagnosed and Treated with New Outpatient Procedure

    Texas Man Who Came to Stony Brook for Minimally Invasive Salivary Gland Treatment
    Abraham Blass looked for a solution to his
    problem and found it at Stony Brook.

    Abraham Blass, 59, of Houston, TX, was having trouble swallowing. It was painful and getting worse. He also experienced recurrent swelling underneath his jaw, especially after eating. Doctors there were unable to make any diagnosis, not even with the aid of a CT scan, and Blass was unable to get the treatment he needed. He had to look elsewhere for better care.

    The man's quest brought him to Stony Brook — some 1,700 miles from home — for salivary endoscopy, the new minimally invasive salivary gland procedure that can be used for both diagnosis and treatment, and that's performed by only a few surgeons in the United States.

    Blass had read online about Stony Brook's head and neck surgeon Mark F. Marzouk, MD, who leads our program in salivary endoscopy. Specially trained in the procedure and with several years of experience, Dr. Marzouk is attracting patients from around the world who come to Stony Brook for this care.

    Blass was treated in early April. During the procedure, Dr. Marzouk was able to make the diagnosis of salivary duct narrowing and also treat the problem at the same time. His narrowing was cured by the doctor using a balloon about one-eighth of an inch in size to dilate (widen) the duct. The procedure was done under local anesthesia with mild sedation and no incisions in the neck.

    "I am doing well so far. No swallowing difficulties and the small nodule under my neck continues to shrink."

    Blass tolerated the procedure well. In fact, he was able to fly back home to Texas the same day. This made the experience for him all the more positive.

    "Mr. Blass's story is not uncommon," explains Dr. Marzouk. "As salivary endoscopy has evolved, many challenging cases have been encountered in which a diagnosis cannot be made with physical exam and imaging modalities."

    Commenting on the care he received at Stony Brook, Blass says, "I highly recommend the sialendoscopy procedure. It was done under local anesthesia and less painful than going to the dentist for a tooth filling. Dr. Marzouk and his entire team were friendly, caring, and knowledgeable throughout the entire process."

    In 2010, soon after Dr. Marzouk joined our faculty, he performed the first salivary endoscopy ever done on Long Island. This minimally invasive technique allows for the examination of the salivary ducts under endoscopic guidance. Treatments, such as stone removal, duct dilatation, and steroid injection, can be done at the same time.

    Not only can duct narrowing be diagnosed and treated with salivary endoscopy. Sialolithiasis, or stone(s) in the salivary duct, is the most common disease of the salivary gland for which salivary endoscopy is done.

    Sialolithiasis affects approximately 12 in 1,000 adults. Symptoms include pain, intermittent swelling of the gland, and possibly severe infection.

    The success rate of salivary endoscopy in treating sialolithiasis is over 90%, as reported in the current literature, with less than 5% recurrence. Recovery time is much faster than with an open technique, and patients may return to a normal diet the same day.

    Salivary endoscopy allows for salivary gland surgery in a safe and effective way, and is done on an outpatient basis. The current standard in most institutions for treating salivary duct stones has been surgical removal of the gland that entails an incision in the neck and an overnight stay in the hospital. The conventional "open" operation also carries with it the potential complications of scarring, wound infection, and nerve injury.

    Originally developed in Switzerland, the salivary endoscopy procedure is truly one of the most fascinating and patient-centered innovations introduced in the recent years in the field of otolaryngology-head and neck surgery.

    Stony Brook Medicine is the only institution in both Nassau and Suffolk counties currently providing this truly state-of-the-art service to patients. Read more about salivary endoscopy.

  • Minimally Invasive Surgery for Esophageal Cancer Is Better for Patients, Finds Trial

    By Kevin T. Watkins, MD, Chief of Upper Gastrointestinal and General Oncologic Surgery

    The British journal The Lancet just published a report online of a clinical trial with impressive findings that demonstrate not only is minimally invasive surgery to remove the esophagus of patients with esophageal cancer an operation that's easier on the patient, it can also greatly reduce the risk of pulmonary (lung) infection compared to traditional open surgery.

    The report, titled "Minimally Invasive versus Open Oesophagectomy for Patients with Oesophageal Cancer," details a multi-center trial conducted by Dutch researchers.

    In addition to their clinical observations, these researchers found that patients who undergo the mlnimally invasive procedure have much shorter hospital stays and a better short-term quality of life than those who have open surgery.

    They studied the outcomes of 56 patients who had open surgery and 59 patients who had the minimally invasive procedure. The different operative techniques were deemed equally effective in treating the cancer.

    Thirty-four percent of patients in the open surgery group had a pulmonary infection while in the hospital, compared with 12% of patients in the minimally invasive group. Two weeks post-op, pulmonary infections occurred in 29% of those in the former group but only 9% of those in the latter group.

    One of the key reasons we perform minimally invasive surgical procedures in general
    is because there are fewer pulmonary complications associated with them.

    There have been many trials looking at minimally invasive surgical procedures. This trial is a very well-designed study from the standpoint that it is a prospective randomized trial with an intention to treat analysis.

    In the United States, a trial like this would be difficult, at best, to accomplish since most patients wouldn't agree to possibly randomize to the open procedure. In a patient-driven market, they seek the minimally invasive approach even if there are no documented benefits.

    In this trial, only a few patients who were randomized to undergo the open procedure refused to proceed in the trial, which was good. The conclusions of a lowered pulmonary complication rate justify one of the key reasons we perform minimally invasive surgical procedures in general.

    Improved pulmonary function after laparoscopic procedures has been shown in the past. The one point the authors of the present report did not highlight as much as I would have hoped was the increased vocal cord paralysis rate in the patients having open surgery.

    I have previously published in a small series that we under-report vocal cord paralysis after open procedures (see "Analysis of Respiratory Complications after Minimally Invasive Esophagectomy: Preliminary Observation of Persistent Aspiration Risk." Dysphagia 2007;22:49-54).

    Since the vocal cords are what have to close down to prevent aspiration, the increased injury rate associated with open procedures may significantly increase the pulmonary infection rate, and not for the reasons the authors propose.

    The authors documented that all vocal cord injuries were seen on laryngoscopy, but didn't state that all patients had laryngoscopy to evaluate their cords. One could actually conclude that the majority of the pulmonary complications occur with this procedure because of vocal cord injury.

    The minimally invasive procedure was first used two decades ago but this is the first study to compare minimally invasive and open esophagectomy, according to Dr. Miguel A. Cuesta, senior author of the report, and his co-authors.

    "If these results can be confirmed in other settings, minimally invasive esophagectomy could truly become the standard of care," Dr. Simon Y.K. Law, of the University of Hong Kong, states in an accompanying editorial published in the journal.

    Click here to read the abstract of the study on the website of The Lancet.

  • May Is National Trauma Awareness Month — Time to Think about Injury Prevention

    Our Trauma Team Being Filmed by The Learning Channel
    Our trauma team being filmed by The Learning
    Channel for a program focusing on trauma care
    "starring" Stony Brook's Level 1 trauma center.
    May is National Trauma Awareness Month that features the annual campaign to promote safety on our roads, in our work, and at our homes. In observance of it, our trauma team wants to share a set of facts provided by the American Trauma Society.* Take heed of them each day of this month, and be safe!

    Day 1: Injuries are the number one cause of death among children. Car crashes, suffocation, drowning, poisoning, fires, and falls are some of the most common causes of injury.

    Day 2: Every hour, one child dies from an injury.

    Day 3: Car crashes, suffocation, drowning, poisoning, fires, and falls are some of the most common ways children are hurt or killed. Though death rates for most of these are dropping, suffocation and poisoning rates are on the rise.

    Day 4: About one in five child deaths is due to injury.

    Day 5: Every 4 seconds, a child is treated for an injury in an emergency department.

    Day 6: Each year, one in every three adults age 65 and older falls. Falls can cause moderate to severe injuries, such as hip fractures and head traumas, and can increase the risk of early death.

    Day 7: Among older adults (those 65 or older), falls are the leading cause of injury death. They are also the most common cause of nonfatal injuries and hospital admissions for trauma.

    Day 8: Falls are the most common cause of traumatic brain injury (TBI). In 2000, TBI accounted for 46% of fatal falls among older adults.

    Day 9: Many people who fall, even if they are not injured, develop a fear of falling. This fear may cause them to limit their activities leading to reduced mobility and loss of physical fitness, which in turn increases their actual risk of falling.

    Stony Brook University Hospital is the only designated Level 1 trauma center in Suffolk County.

    Day 10: The chances of falling and of being seriously injured in a fall increase with age. In 2009, the rate of fall injuries for adults 85 and older was almost four times that for adults 65 to 74.

    Day 11: Motor vehicle crashes are the leading cause of death among those aged 5-34 in the United States.

    Day 12: The economic impact is also notable: the lifetime costs of crash-related deaths and injuries among drivers and passengers were $70 billion in 2005.

    Day 13: U.S. adults drank too much and got behind the wheel about 112 million times in 2010.

    Day 14: Alcohol-impaired drivers are involved in about one in three crash deaths, resulting in nearly 11,000 deaths in 2009.

    Day 15: Motor vehicle crashes are the leading cause of death among those aged 5-34 in the United States.

    Day 16: Adult seat belt use is the most effective way to save lives and reduce injuries in crashes. Yet millions of adults do not wear their seat belts on every trip.

    Day 17: Motor vehicle crashes are the leading cause of death for U.S. teens, accounting for more than one in three deaths in this age group. In 2009, eight teens ages 16 to 19 died every day from motor vehicle injuries. Per mile driven, teen drivers ages 16 to 19 are four times more likely than older drivers to crash.

    Day 18: Compared with other age groups, teens have the lowest rate of seat belt use. In 2005, 10.2% of high school students reported they rarely or never wear seat belts when riding with someone else.

    Day 19: In 2008, 4,378 pedestrians were killed in traffic crashes in the United States, and another 69,000 pedestrians were injured. This averages one crash-related pedestrian death every 2 hours, and a pedestrian injury every 8 minutes.

    Day 20: Pedestrians are 1.5 times more likely than passenger vehicle occupants to be killed in a car crash on each trip.

    Day 21: Alcohol-impairment: either for the driver or for the pedestrian: was reported in 48% of the traffic crashes that resulted in pedestrian death. Of the pedestrians involved, 36% had a blood alcohol concentration (BAC) above the illegal limit of 0.08 grams per deciliter (g/dL) or higher.

    Day 22: Each day, more than 15 people are killed and more than 1,200 people are injured in crashes that were reported to involve a distracted driver.

    Day 23: There are three main types of distracted driving:

    • Visual: taking your eyes off the road;
    • Manual: taking your hands off the wheel; and
    • Cognitive: taking your mind off what you are doing.

    Day 24: In 2009, more than 5,400 people died in crashes that were reported to involve a distracted driver and about 448,000 people were injured. Among those killed or injured in these crashes, nearly 1,000 deaths and 24,000 injuries included cell phone use as the major distraction.

    Day 25: Twenty-five percent of drivers in the United States reported that they "regularly or fairly often" talk on their cell phones while driving.

    Day 26: Nine percent of drivers in the United States reported texting or emailing "regularly or fairly often" while driving.

    Day 27: Every day, almost 30 people in the United States die in motor vehicle crashes that involve an alcohol-impaired driver. This amounts to one death every 48 minutes.

    Day 28: In 2008, an estimated 7,000 people — an average of more than 19 people every day — were treated in emergency departments for injuries sustained from fireworks, and more than half of those injured were children.

    Day 29: The annual cost of alcohol-related crashes totals more than $51 billion.

    Day 30: The leading causes of TBI are:

    • Falls (35.2%);
    • Motor vehicle — traffic (17.3%);
    • Struck by/against events (16.5%); and
    • Assaults (10%).

    Day 31: Prevention works!

    • Seat belts have saved an estimated 255,000 lives between 1975 and 2008.
    • School-based programs to prevent violence have cut violent behavior among high school students by 29%.
    • Sobriety checkpoints have been shown to cut alcohol-related crashes and deaths by about 20%.
    • Tai chi and other exercise programs for older adults have been shown to reduce falls by as much as half among participants.

    For information about injury prevention programs in Suffolk County, please email our trauma nurse coordinator Jane E. McCormack. For injury prevention strategies, visit the National Center for Injury Prevention and Control.


    * For the information in this post we thank the American Trauma Society, which is dedicated to the prevention of trauma and improvement of trauma care.

  • JAMA Report Raises Concerns about Popular Breast Cancer Treatment: Are They Valid?

    By Brian J. O'Hea, MD, Chief of Breast Surgery

    Traditional post-lumpectomy radiation involves whole breast radiation therapy (WBRT). WBRT is delivered as external beam therapy five days a week for six or seven weeks. Mammosite radiation delivers partial breast irradiation (PBI) by an external catheter and a radioactive seed (brachytherapy). This technique only radiates the immediate lumpectomy area, and can be completed in five days.

    This data was first presented at the annual San Antonio Breast Cancer Conference last December, and drew the attention of The Wall Street Journal, which published an article about it titled "New Scrutiny for Popular Breast-Cancer Treatment."

    The current study just published in The Journal of the American Medical Association is a very large retrospective analysis comparing the two types of treatment, and to date, it is the largest study of its kind.

    The results show a higher breast recurrence rate (resulting in mastectomy) in patients who had PBI with Mammosite compared to women who had conventional WBRT.

    The results of this study should not dissuade interested women from pursuing the option
    of partial breast irradiation following surgery for breast cancer, if they are good candidates for it.

    The researchers concluded that treatment with brachytherapy compared with WBI was associated with worse long-term breast preservation rates. Survival rates were the same in both groups.

    Although the recurrence rate was higher with PBI versus WBRT, the overall recurrence rates were very low in both groups (3.95% PBI versus 2.18% WBRT).

    What this study really shows is that five years after lumpectomy and PBI, only 4% of women will need mastectomy because of breast cancer recurrence. Now that's a low number! Infection rates with PBI are approximately 5%, and rib fractures are very rare in experienced centers, such as Stony Brook University Hospital.

    The results of this study should not dissuade interested women from pursuing the PBI brachytherapy option.

    PBI with Mammosite catheter remains a very viable option for specially selected patients with adequate breast size, and small, low-risk breast cancers, who prefer a much shorter, more convenient radiation alternative. But the Mammosite option has to be discussed before surgery, so if you are interested, be sure to find a surgeon who will offer this option.

    "There is nothing in our study saying that a woman should not choose brachytherapy if they want the convenience," says study author Dr. Benjamin D. Smith, as quoted in HealthDay. "Our study really emphasizes that we need to continue to enroll patients in trials to try to evaluate the technology."

    Click here to read the abstract of the study on the JAMA website.

  • New Study Finds Lower Risk for Bowel Obstruction with Minimally Invasive Surgery

    By Paula I. Denoya, MD, of the Stony Brook Colon and Rectal Surgery Division

    A report just published in Archives of Surgery, titled "Effect of Laparoscopy on the Risk of Small-Bowel Obstruction," details a study of the effect of laparoscopy on the risk of bowel obstruction. Laparoscopy, or minimally invasive surgery, allows the surgeon to use a video camera and long thin instruments to perform complex surgery through several tiny incisions rather a large one.

    The laparoscopic technique has several advantages, including generally faster recovery after surgery and less scarring. It is also believed that laparoscopy may cause less trauma to the intestines during surgery, which may prevent the formation of internal scar tissue called adhesions.

    Adhesions can cause kinking and twisting of the intestine, leading to blockages, months to years after the initial operation.

    The researchers who conducted the study looked at a registry kept by the Swedish National Board of Health, which keeps track of all hospitalizations of Swedish residents. They studied a total of 108,141 patients who underwent common operations and compared the ones who had conventional open surgery and the ones who had laparoscopic surgery.

    Use of laparoscopy may help to prevent the future complication of bowel obstruction.

    They found that several factors including age, previous abdominal surgery, other medical problems, and the use of open surgery rather than laparoscopy all increased the risk of being hospitalized for a bowel obstruction in the future.

    The researchers' conclusions are valid with some limitations. The number of patients studied is very large, and the information on each patient is recorded into the Registry prospectively, meaning at the time that it happens, which increases the likelihood that what is recorded is accurate.

    However, the study looked at the data recorded previously and did not look into each patient's individual chart, so certain other factors which may influence the risk of obstruction may not be taken into account accurately.

    Also, the percentage of open or laparoscopic surgeries that were done for certain types of operations were not equal. For example, most of the appendix surgeries were performed laparoscopically, whereas only 1-2% of colon surgery was performed laparoscopically, making it difficult to compare results.

    The take-home message is that use of laparoscopy, along with several other factors, may help to prevent the future complication of bowel obstruction, but that the amount of risk reduction is still unclear and there is room for further study.

    The new study appears in the April issue of Archives of Surgery. "This study shows that, beyond important factors such as age, previous abdominal surgery, and co-morbidity [co-existing illnesses], the surgical technique is the most important factor related to [small-bowel obstruction]," say the researchers in a news release from Archives of Surgery.

    "For surgeons, [the study] highlights another potential benefit of minimally invasive surgery and challenges us to continue to offer less invasive procedures whenever they are feasible," Dr. Luke Funk and Dr. Stanley Ashley, gastrointestinal surgeons at Harvard Medical School, say in their comment on the study that appears in an accompanying editorial published in the journal.

    Click here to read the abstract of the study provided by the National Library of Medicine.

  • Kids' Accidental Death Rates Down 30% Nationally with Similar Trend in Suffolk County

    New Report from CDC Shows Improvements in Child Safety, As Found As Well in Our Community

    Fewer kids have died from accidents over the past decade in the United States, according to a new report from the U.S. Centers for Disease Control and Prevention that was just released last week. This is very good news.

    The CDC says death rates from kids between the ages of 0 and 19 have dropped 30% between 2000 and 2009. One major reason was a 41% decline in traffic fatalities, which annually account for half or more of kids' deaths caused by accidents. Childhood deaths from drowning, fires, and falls also dropped significantly. But "more can be done to keep our children safe" says the report.

    Suffolk County is keeping apace with the national trend, with fewer accident admissions among children and adolescents, thanks in part to our accident prevention outreach programs. The 2007-11 data from the New York State Trauma Registry for Suffolk County show a continuing decline of 28% in pediatric accident admissions.

    Suffolk County has likewise seen a significant decline in kids injured in accidents,
    with fewer accident admissions occurring annually in recent years.

    "Kids are safer from injuries today than ever before," CDC director Thomas Frieden said in a written statement. "In fact, the decrease in injury death rates in the past decade has resulted in more than 11,000 children's lives being saved. But we can do more. It's tragic and unacceptable when we lose even one child to an avoidable injury," he said.

    Thomas K. Lee, MD, chief of pediatric surgery, emphasizes that unintentional injuries are the number one killer of children in the nation. Commenting on the CDC report, he explains, "Improvement in trauma medical care contributes to the decreasing death rates."

    Dr. Lee further emphasizes that Stony Brook Children's is the only hospital in Suffolk County that has all the pediatric specialists who can offer the state-of-the-art trauma management." (Read about the pediatric trauma program.)

    At Stony Brook Long Island Children’s Hospital, we don’t just take care of kids
    who are injured in accidents; we promote child safety, as well.

    "Motor vehicle accidents in Suffolk County continue to be the major reason for injury among older kids, but we have seen a significant reduction in the number of teens injured in them," says our trauma nurse coordinator Jane E. McCormack, who is active in Stony Brook Children's accident prevention outreach programs.

    She believes that strengthening of the New York State Graduated License Law for young drivers, as well as our accident prevention outreach programs — namely, her own program (see Keeping Teen Drivers Safe: What Parents Can Do) and the Suffolk County Safe Kids Coalition — are the major reasons why Suffolk County has fewer accident admissions and deaths annually in recent years.

    Stony Brook Children's is the lead organization of Safe Kids Suffolk County, a coalition that involves partnerships with both public and private organizations whose sole purpose is to prevent death and injuries to children. Unintentional injuries are the number one killer of children in our community, with motor vehicle accidents causing the most deaths.

    "Local statistics direct our efforts toward occupant protection programs, traumatic brain injury prevention strategies, and water safety initiatives," explains Susan Katz, coordinator of Safe Kids Suffolk County, adding: "The coalition is successful because of the many dedicated volunteers and professionals with a passion to protect children and assure they have the safest environment to grow and strive in." Learn how you can help save lives and prevent injuries to our kids.

    For information about the programs of the Safe Kids Suffolk County Coalition, please call Susan Katz at 631-444-7470.

  • Stony Brook Surgery Top Doctors: Focus on Plastic and Hand Surgeon Dr. Jason C. Ganz

    Jason C. Ganz, MD, joined our faculty four years ago as a member of our Plastic and Reconstructive Surgery Division. He came to Stony Brook from New York Medical College, where he practiced at Westchester Medical Center in Valhalla, NY.

    Previously, Dr. Ganz had been on the faculty of Case Western Reserve University in Cleveland, OH, and on staff at University Hospitals/Case Western Medical Center, as well as at Louis Stokes Cleveland Veterans Affairs Medical Center, where he was chief of plastic surgery.

    Board certified in plastic surgery and hand surgery, Dr. Ganz focuses his practice on reconstructive and aesthetic surgery and on hand surgery, including treatment of hand and wrist disorders, fractures, tendon injury, and nerve injury or compression (carpal tunnel syndrome).

    Since joining our faculty in 2008, Dr. Ganz has made news on more than one occasion, performing rare and complicated limb reattachment surgery as well as toe-to-thumb transplant surgery, both requiring the most sophisticated reconstructive microsurgical expertise.

    Dr. Ganz is a specialist in microsurgery; limb reattachment; breast reconstruction after cancer, breast reduction, and breast augmentation; nose surgery; treatment of facial fractures; reconstructive surgery for burn patients; facelift, general liposuction, and tummy-tuck surgery; and evaluation and surgical management of chronic wounds (skin grafting and soft-tissue flap coverage).

    Dr. Ganz received his MD in 1998 from New York Medical College, where his outstanding performance earned him election to the Alpha Omega Alpha Honor Medical Society. He was trained in plastic surgery at Georgetown University in Washington, DC. Subsequently, he completed his fellowship training in hand surgery in the orthopaedics department here at Stony Brook.

    Watch this news clip (2:03 min) aired on WPIX TV News about Dr. Ganz's successful 11-hour operation reattaching a severed hand (caution — graphic images):

  • Beating Cells in Our Cardiac Lab — Toward a Cure for Heart Attacks

         

    We'd like to offer a glimpse of one of the projects now underway in our cardiac research lab, which aims to find a means to cure heart attacks.

    Our cardiac lab, under the direction of Todd K. Rosengart, MD, chairman of surgery, is one of only 25 NIH-funded cardiac surgery labs of its kind in the country.

    Watch our short video (~1 min) to see genetically-engineered cells that turned into muscle cells and began to beat spontaneously. It's life in a Petri dish!

    This basic science work was done in collaboration with Yupo Ma, MD, PhD, of pathology. Learn more about our cardiac lab >

  • Treating GERD Helps Sleep, According to New Study Led by Member of Our ENT Team

    Findings of News-Making Report Offer Hope for Many Afflicted with Sleep Disturbance Disorder

    Elliot Regenbogen, MD | Otolaryngologist
    Dr. Elliot Regenbogen

    The use of proton pump inhibitors (PPIs) improves the sleep and daytime quality of life for sufferers of gastroesophageal reflux disease (GERD), according to a systematic literature review conducted by Elliot Regenbogen, MD, of our Otolaryngology-Head and Neck Surgery (ENT) Division, and colleagues here at Stony Brook Medicine. This research demonstrates our commitment to advancing patient care.

    The report, titled "Esophageal Reflux Disease Proton Pump Inhibitor Therapy Impact upon Sleep Disturbance," was just published in the April issue of Otolaryngology-Head and Neck Surgery.

    A 2003 Gallup survey linked GERD — also known as heartburn or reflux esophagitis — with frequent sleep disturbances. PPIs have proven to be an effective treatment therapy, and there are established criteria for treating reflux. However, there are no well-established clinical guidelines on how to treat the sleep disturbances with the resulting quality-of-life issues.

    The objective of Dr. Regenbogen's review was to evaluate the impact of PPI treatment of GERD on sleep disturbance-related outcomes, as documented in the medical literature.

    In addition to Dr. Regenbogen who is the first author, the co-authors of the report are Alex Helkin and Rachel Georgopoulos, two senior medical students in the School of Medicine; Tajender Vasu, MD, of the Pulmonary, Critical Care, and Sleep Medicine Division; and A. Laurie W. Shroyer, PhD, MSHA, vice chair of research of the Department of Surgery.

    Together, the authors performed a systematic literature review using three databases — PubMed, Web of Science, and Cochrane Library — of all randomized placebo-controlled clinical trials from 1989 (when omeprazole became available) to October 2011. Additional relevant publications were identified based on the articles' citations.

    The search strategy identified all randomized placebo-controlled clinical trials published in English; both PPI use and outcome measures of sleep disturbance were reported for GERD patients. Using a pre-established systematic review protocol and data extraction format, the four co-authors independently reviewed all articles.

    Findings of our study support the use of PPI medications as a treatment to improve GERD symptoms
    and associated quality-of-life sleep disturbance-related outcomes.

    Based on the review findings, the authors state in the report: "The existing evidence supports the use of PPI medications as a treatment to improve esophageal reflux disease symptoms and associated quality-of-life sleep disturbance-related outcomes."

    "Although the improvements are likely secondary gains from reduction or elimination of nocturnal GERD symptoms, further research appears warranted to evaluate PPI treatment impact on polysomnography outcomes, as well as to examine the relationship of polysomnography versus nonpolysomnography outcomes, for GERD patients with sleep disturbance and sleep-disordered breathing," they add.

    Dr. Regenbogen explains the value of the approach he used to conduct the study, as it relates to evidence-based medicine and high-quality healthcare:

    "A systematic review of the literature presents a structured summary and critical appraisal of high-quality research evidence relevant to a focused question. Systematic reviews of high-quality randomized controlled trials are crucial to evidence-based medicine, and have become a cornerstone in the development of high-quality healthcare. The scope of systematic reviews is not limited to direct medical interventions but may also concern issues regarding public health and economic impact.

    "To achieve this level of quality, the search strategy of a systematic review is clearly described, exhaustive, transparent, and reproducible. The databases and citation indexes, in this case PubMed, Web of Science, and the Cochrane Library, are searched, and studies meeting pre-stated criteria pertaining to the research question are included.

    "By using an objective and transparent approach for research synthesis interpretation of results by the multiple reviewers involved are less prone to bias. The purpose of a review is synthesis: combine the reports from to create a 'greater whole.'"

    Otolaryngology-Head and Neck Surgery is the official scientific journal of the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS), one of the oldest medical associations in the nation, which represents nearly 12,000 physicians and allied health professionals who specialize in the diagnosis and treatment of disorders of the ears, nose, throat, and related structures of the head and neck.

    About Dr. Elliot Regenbogen

    Dr. Regenbogen joined our Otolaryngology-Head and Neck Surgery Division in 2009 as assistant professor of surgery. He came to Stony Brook from Westchester County, where he had practiced general otolaryngology for 17 years, and also served as chairman of the otolaryngology department at Northern Westchester Hospital.

    Dr. Regenbogen focuses his clinical practice on general otolaryngology-head and neck surgery, as well as on advanced diagnosis and treatment of voice and swallowing disorders. His practice also includes the diagnosis and treatment of chronic sinus conditions, postnasal drip, nasal obstruction, allergy, loss of smell and taste, reflux esophagitis, snoring and sleep apnea, hearing loss, and ear infections.

    In addition to reflux esophagitis and its related sleep disturbance, Dr. Regenbogen's research interests include the development of ultra-high resolution immunofluorescent-based imaging systems for the detection and treatment of benign and malignant disorders of the vocal cords, head and neck, and paranasal sinuses.

    The news-making report on PPIs and GERD, which is a model of the systematic literature review,
    reflects the specialized training that Dr. Regenbogen gained as a Cochrane Scholar.

    Dr. Regenbogen received his MD in 1986 from Albert Einstein College of Medicine, where he subsequently completed his residency training. His training included a preceptorship at Japan's Kurume University Hospital under Minoru Hirano, MD, PhD, one of the founders of modern concepts in laryngology, as well as collaboration with Wilbur J. Gould, MD, and Stanley M. Blaugrund, MD, at the Ames Vocal Dynamics Laboratory of Lenox Hill Hospital in New York.

    In 2010, Dr. Regenbogen was honored by his selection to receive a Cochrane Colloquium Grant and work as a Cochrane Scholar. The AAO-HNS annually provides three competitive travel grants to facilitate attendance at the annual Cochrane Colloquium for training in the conduct and publication of systematic literature reviews, with focus on state-of-the-art techniques for producing systematic reviews and meta-analyses.

    Click here to see the abstract of the Regenbogen report on PubMed provided by the National Library of Medicine. And, watch this short video (0:54 min) to see how PPIs work:

  • Two Members of Department Elected to Alpha Omega Alpha National Honor Medical Society

    We are proud to announce that Sami U. Khan, MD, associate professor of surgery, and Brett T. Phillips, MD, clinical assistant instructor of surgery (third-year resident), have just been elected by Stony Brook School of Medicine's Class of 2012 to membership in the prestigious Alpha Omega Alpha Nataional Honor Medical Society.

    "This is a singular honor," says Todd K. Rosengart, MD, chairman of surgery, "and well reflects Dr. Khan's and Dr. Phillips's significant contributions to the academic mission of our institution. They join our two most recent other inductees, Drs. Emily Wood and Michael Polcino, in earning this distinction. This selection is a wonderful and well-deserved affirmation of the great accomplishments of these members of our department."

    Richard J. Scriven, MD, director of the general surgery residency program, adds: "I would also like to point out that the graduating medical school class only inducted four people, out of all the attendings and residents at our institution. The fact that we have two of these four speaks to the excellent educational role models of our department."

    Sami U. Khan, MD | Stony Brook Plastic Surgeon
           
    Alpha Omega Alpha Honor Medical Society
           
    Brett T. Phillips, MD
    Dr. Brett T. Phillips

    Alpha Omega Alpha, founded in 1902, is the national medical honor society. Election to the society is a high honor signifying a lasting commitment to scholarship, leadership, professionalism, and service.

    A lifelong honor, membership in Alpha Omega Alpha confers recognition for
    a physician's dedication to the profession and art of healing.

    Alpha Omega Alpha is to medicine what Phi Beta Kappa is to letters and the humanities, and Sigma Xi is to science. The society's values include honesty, honorable conduct, morality, virtue, unselfishness, ethical ideals, dedication to serving others, and leadership. Members have a compelling drive to do well and to advance the medical profession and exemplify the highest standards of professionalism.

    Nationwide, about 3,000 students, alumni, house staff, and faculty are elected each year. Since its founding, more than 150,000 members have been elected to the society.

    Click here to see a slideshow about Alpha Omega Alpha, with focus on its history and present programs.

  • FAQs about Traumatic Brain Injuries and How to Prevent Them

    With the arrival of spring come more opportunities for outdoor activities, some of which pose a risk for traumatic brain injuries. These injuries can be serious. According to the Centers for Disease Control and Prevention, they are responsible for an estimated 1.7 million deaths, hospitalizations, and emergency department visits each year in the United States, and they are contributing factor to a third of all injury-related deaths in this country.

    Here, Marc J. Shapiro, MD, one of the leaders of our trauma/surgical critical care service, discusses what you need to know about traumatic brain injuries and, most important, how to prevent them.

    Q: What is a traumatic brain injury?

    A: A traumatic brain injury, which we call TBI for short, is any injury that occurs to the brain — often leading to devastating consequences that keep individuals from functioning at the same level as before the event occurred.

    Most common causes of TBI include motor vehicle accidents, falls, and sports-related trauma. Despite multiple methods used to lower the incidence, TBI rates in the United States are on the rise.

    Q: What can be done to help prevent TBI?

    A: In many cases, TBIs can be prevented. There are many simple things an individual can do:

    • If you ride a motorbike or motorcycle, wear a helmet. Statistics show that the number and severity of head injuries decrease with helmet use. States that have repealed their helmet laws show an increase in head injuries and, ironically, organ donation. Also, be sure that the helmet is crash-certified by the appropriate federal agencies.
    • If you ride a bicycle, wear a helmet. It is estimated that between 74% and 85% of all bicycle-related head injuries could be prevented with helmets.
    • Other outdoor activities that require wearing a proper helmet are using in-line skates, riding a skateboard or scooter, riding horses, and batting and running bases when playing baseball or softball.
    • Avoid falls from ladders when outdoors by not using them during adverse weather conditions (e.g., high wind, rain) and when indoors by using a step-stool with a grab bar to reach objects on high shelves. Falls from portable ladders — step, straight, combination, and extension — are the cause of many TBIs. (See safety guidelines provided by U.S. Consumer Product Safety Commission.)
    • Implement fall prevention strategies for children (tips here) and for seniors (tips here).
    • Avoid drinking and driving. Alcohol is a factor in 50% of motor vehicle accidents where a death occurs. Not only does alcohol affect reaction time when driving, it could also interfere with the healthcare provider’s ability to assess and treat you properly.
    • If you are taking any type of narcotic medication, ask your doctor if it is okay for you to drive. In fact, it is a good idea to ask your doctor this question when you start any new medications, as many can impair judgment and slow reaction times.
    • Be sure that your car has a three-point restraining seatbelt; that is, one that has both a lap and shoulder component, and wear it at all times. During an accident, in order for the airbags to work properly you must be wearing a seatbelt. Otherwise, the deployed airbag acts as a kind of lever that can catapult passengers through the windshield.

    Q: What are the symptoms of a traumatic brain injury, and when is it time to seek medical attention after a head injury?

    A: TBI can have different kinds of physical and psychological effects. There is a wide range of symptoms associated with it. Some may appear right after the traumatic injury, while others may appear days or weeks later. (See partial list of symptoms.)

    Watch for headaches, visual disturbances, droopy eyelids, or problems with arm or leg function. Should any of these symptoms emerge after any kind of blow to the head, call your physician immediately or go to an emergency room.

    Q: How does Stony Brook University Hospital approach TBIs?

    A: First and foremost, we advocate prevention and participate in a number of community initiatives aimed at preventing accidental injury, such as Safe Kids. However, if a brain injury occurs, you should know that Stony Brook is the only Level 1 Trauma Center in Suffolk County and a leader in trauma care — not just in New York, but in the nation.

    Stony Brook was recently recognized among the top four percent of trauma centers nationally, as well as the top hospital in the country for treating pedestrians who have been hit by motor vehicles. In addition, Stony Brook coordinates trauma services for all of Suffolk County, and is instrumental in setting and maintaining the standard of care.

    With sophisticated diagnostics and a collaborative, multidisciplinary team composed of emergency physicians, trauma surgeons, orthopedic surgeons, neurosurgeons, other specialists as needed, nurses, critical care doctors, and respiratory, physical, and occupational therapists, Stony Brook takes a comprehensive approach to all injuries, especially brain injuries.

    Because a brain injury can worsen once it occurs, Stony Brook uses a number of early interventions to relieve pressure on the brain, such as draining fluid from the brain to decrease damage from swelling and to keep blood flow to the brain from being compromised.

    Once patients are medically stable and can be discharged, Stony Brook physicians continue to monitor them, whether they are discharged home or to a rehabilitation center, to ensure that patients can return to as close to a pre-injury condition as possible. There is no greater gratification than when our patients visit with our healthcare team after making a remarkable recovery.

    For more information about TBIs and how to prevent them, visit the Brain Trauma Foundation and the Centers for Disease Control and Prevention, and also see the NINDS Traumatic Brain Injury Information Page.

  • Understanding New York State's Reporting of Heart Surgery Outcome Data — When a List Is Not a List

    By Todd K. Rosengart, MD, Chairman of Surgery and Chief of Cardiothoracic Surgery

    The recent publication of the New York State Department of Health annual report on cardiac procedure outcomes marks a 20th anniversary of this report — one of the first of its kind in the nation — which first published 1992 cardiac surgery statistics. This occasions a look back on tremendous progress made, both in the adoption of this report as a benchmarking tool in New York and nationally, and as a barometer of progress in improving the quality of cardiac care.

    One of the important goals of this reporting system was to ensure that significant outliers in cardiac surgery quality were identified, and potential deficiencies addressed.

    This 20th anniversary marks tremendous progress toward this goal. Four institutions had coronary bypass mortality greater than 4% (and as high as 7%) in the State’s first two annual reports. None were greater than 4% in this year's report. Only two institutions are currently reported at over 3%, compared to eight in 1994.

    Moreover, as compared to 12 "high volume" surgeons (more than 150 cases bypass cases over three years) with mortality rates over 3.5% in the original State report, there were only four such surgeons in this year's report. (Disclaimer: the number of "low volume" surgeons with higher calculated mortality rates has increased during this time period.)

    One important goal of the New York's reporting was to ensure that significant outliers
    in quality surgery were identified, and potential deficiencies addressed.

    Outcomes for heart surgery have, notably, improved nationally as well during this time period, and overall State mortality rates have only decreased from 2.8% to 1.8%, but these data must nevertheless be viewed as a major advance towards "raising the bar" in the performance of cardiac surgery in New York State. As reflected in the State report, access to excellent quality in the performance of cardiac procedures is nearly universal in our State. There is, however, a cautionary tale that must be considered before our wholehearted celebration of this success. A case in point:

    A 91-year-old gentleman with a very active life style and a very supportive family suffers a massive heart attack on Christmas, 2011, and is rushed to the hospital. He undergoes an emergency procedure during which doctors place him on an artificial pumping machine for life support. Heart surgeons are called to decide whether he is a candidate for emergency coronary bypass surgery. Because of the location of the blockage in his heart arteries, the surgery represents the best option for recovery.

    The surgeons meet a vibrant, pleasant but very worried patient and a very concerned family. Given the patient's age and condition, his chances of not surviving surgery are about seven times (700%) greater than the normal risk, according to a New York State scoring system. Even though it is very high risk, the surgeons find and agree to offer surgery as the best available treatment option.

    The bypass surgery is done, and our 91-year-old patient is doing well today — a happy, and true, story.

    Is public reporting that even results in case selection a bad thing?

    In New York State, though, there is another piece to this puzzle. The results of heart surgery procedures — surgery and angioplasty — are reported publicly in New York on an annual basis. In the case of surgery, this reporting over the past 20 years has been associated with a trend of very significant improvements in outcomes for heart surgery, such that excellent outcomes for angioplasty and heart surgery are available nearly universally in New York. This public reporting has been widely viewed — even by surgeons — as a very good thing.

    Another story, on another day, at another equally "good" hospital: our same 91-year-old patient does not beat the "700%" odds, and unfortunately does not survive surgery. That "Hospital B" had been recording a 99% success rate in survival over 100 previous consecutive coronary bypass procedures for the year. Instead of a 1% mortality rate for the year, Hospital B doubles its observed mortality rate, and with statistical correction nearly doubles its reported "risk-adjusted mortality rate."

    The statisticians will tell you that "Hospital A" and "Hospital B" (or surgeons "A" and "B") are statistically indistinguishable, because adverse cardiac outcomes have become so relatively infrequent that statistical "confidence intervals" do not allow distinctions between the outcomes of these two institutions. To its credit, New York State accordingly no longer lists outcomes based upon the rank order of these complication rates, but alphabetically, including these (typically overlapping) confidence intervals.

    At Stony Brook University Hospital, we are highly regarded for
    our expertise in treating patients in a high-risk state following a heart attack.

    Unfortunately, perhaps because of our competitive nature and our curiosity for lists and "winners," our tendency is to place Hospital B "down the list" from Hospital A based on its numerical mortality "score." Statisticians notwithstanding, Hospital A is then perceived to be "better" — even, "twice as good," as Hospital B (in this case, only because of the different fate of our 91-year-old patient).

    Except perhaps for some bruised egos and "bad publicity," this is perhaps not too big a deal, except that it also engenders a potentially dangerous phenomenon — one of "cherry picking" cases that will minimize the risks considered above. It is hard to know how often this happens, and few if any would admit to such a practice ("the surgery is too risky"). Data to investigate this selection (rationing?) is difficult to gather, but it would have led to our 91-year-old patient being denied the care that proved life-saving.

    Is public reporting that even results in case selection, then, actually a bad thing? To the extent that inferior practices and outcomes have been accurately identified and corrected over the past 20 years in New York State, it is obviously a good thing. It is also a good thing when the light of public reporting minimized the performance of procedures where the hope of success is unjustifiable.

    But it would be a bad thing should patients be denied reasonable risk surgery (10% in the case of our 91-year-old — although seven times the normal 1.5% risk) because of practitioners' concerns that they might not be named an outcomes list "winner" if these data are not carefully and appropriately reported and considered.

    We have in New York seen a good effort at accuracy and transparency for reporting of outcomes for cardiac care made by our Department of Health. It will remain important to protect this resource by all using the information we are given wisely and carefully.

    Follow Dr. Rosengart on Twitter!

  • Inauguration of the Cedric J. Priebe Jr., MD, Endowed Pediatric Surgery Lectureship

    This week, the Cedric J. Priebe Jr., MD, Endowed Pediatric Surgery Lectureship presented its first program, featuring visiting professor Henri R. Ford, MD, surgeon in chief of Children's Hospital Los Angeles and vice dean of the Keck School of Medicine at the University of Southern California.

    A world-renowned pediatric surgeon, Dr. Ford has demonstrated truly exceptional leadership in pediatric surgery, and has conducted the definitive studies on pediatric trauma in the United States.

    Dr. Ford was active in Haiti in the post-earthquake rescue, for which his expertise in trauma was vital to saving the lives of many there just after the disaster occurred in 2010 (see video clip, Haitian Doctor Returns to His Homeland to Help). He remains active in the recovery and rebuilding efforts there.

    Dr. Ford's investigative studies have generated new insights into the pathogenesis of necrotizing enterocolitis, the most common and the most lethal disorder affecting the gastrointestinal tract of newborn infants.

    Today, because of Dr. Cedric J. Priebe's leadership as our founding chief of pediatric surgery,
    we educate tomorrow's surgeons to provide the best care to children.

    The two-day inaugural program started with Dr. Ford participating in a case presentation conference with our medical students and surgical residents.

    On the morning of the second day, Dr. Ford gave the Cedric J. Priebe Jr., MD, Endowed Pediatric Surgery Lecture, titled "The Molecular Basis for the Pathogenesis of Necrotizing Enterocolitis," as part of our weekly Surgical Grand Rounds lecture series. The lecture focused on his leading-edge basic and translational research aimed at improving patient care.

    Dr. Priebe himself participated in all the events with Dr. Ford, further demonstrating his tireless commitment to the education of our students and residents, on subjects related to pediatric surgery.

    About the Priebe Lectureship

    Dr. Cedric J. Priebe with Patient
    Dr. Priebe with patient (click
    on photo for his bio).

    The launch of our campaign to establish the Cedric J. Priebe Jr., MD, Endowed Pediatric Surgery Lectureship took place in the spring of 2010. The Priebe Lectureship supports an annual visiting professor's presentation centering on a current clinical or research issue in pediatric surgery.

    Support of the lectureship fund with charitable donations to the Stony Brook Foundation will help recognize the contribution of Dr. Priebe to pediatric surgical care for Long Island children and his long-standing educational commitment.

    Dr. Priebe, who retired in 2007 from our full-time faculty, was the founding chief of our Pediatric Surgery Division. He started this division in 1982, and served as its chief for 25 years.

    Now, with more than 3,000 outpatient visits and more than 1,000 surgeries annually, we have the largest pediatric surgery program in Nassau and Suffolk Counties.

    Dr. Priebe's sustained desire to constantly improve the surgical care of children has been the dominant force guiding his life. Currently a member of a part-time faculty, he remains committed to our academic mission of excellence.

    Thomas K. Lee, MD, our current chief of pediatric surgery, says, "The Priebe Lectureship will contribute to the strength of our educational program, and its inauguration was a tremendous event. It was clear that both students and residents were greatly stimulated by what they learned from Dr. Ford, our distiguished visiting professor."

    Learn how you can support the Priebe Pediatric Surgery Lectureship endowment fund and, thereby, help advance the education of surgeons caring for children.

  • Studies Confirm Bariatric Surgery Is Better Than Medical Care for Treating Diabetes

    By Aurora D. Pryor, MD, Director, Bariatric and Metabolic Weight Loss Center

    We now have evidence to support what we believe: bariatric surgery is better than medical care for the treatment of diabetes. In two landmark articles published this week in The New England Journal of Medicine, Dr. Philip Schauer and colleagues from the Cleveland Clinic and Dr. Geltrude Mingrone and colleagues from the Catholic University of Rome and the Weill Medical College of Cornell University demonstrate improved diabetes remission in surgery patients compared to patients randomized to receive best medical care.

    The observed positive changes relative to diabetes remission may even occur before substantial weight loss, which generally takes weeks to months.

    The Schauer study is a randomized, controlled, single-center study, called the Surgical Treatment and Medications Potentially Eradicate Diabetes Efficiently (STAMPEDE) trial. The co-investigators randomized 150 type 2 diabetic patients with body mass index (BMI) between 27 and 43 and glycated hemoglobin level of less than 7.0% to receive either aggressive medical therapy or surgical management with sleeve gastrectomy or Roux-en-Y gastric bypass (RYGB).

    Subjects were followed every three months for a year with the therapeutic goal of a glycated hemoglobin level of 6.0% or less. Ninety-three percent of patients completed the 12-month study and were analyzed for outcomes. The therapeutic goal was met in 5 of 41 (12%) of medical patients, 21 of 50 (42%) RYGB patients, and 18 of 49 (37%) sleeve gastrectomy patients.

    All 21 gastric bypass patients who achieved control did so off medication and only 5 of 18 responding (28%) sleeve patients required medication support. Not surprising, the surgical patients also lost more weight than the medical group. In addition, other cardiovascular risk factors (hypertension and hyperlipidemia) improved.

    Type 2 diabetes — closely associated with obesity — is one of the fastest growing epidemics in human history.

    The Mingrone study randomized 60 patients with type 2 diabetes and glycated hemoglobin of less than 7.0 followed for two years to medical therapy or surgery with RYGB or biliopancreatic-diversion (BPD). The end-point of a glycated hemoglobin level of less than 6.5% in the absence of pharmacologic therapy was achieved in no medical patients, compared to 15 of 20 (75 %) RYGB and 19 of 20 (95%) BPD patients. The most common postoperative complication was iron deficiency anemia in 10.5% of patients.

    Dr. Mingrone and colleagues conclude that surgery is preferred to medical management of diabetes: "In severely obese patients with type 2 diabetes, bariatric surgery resulted in better glucose control than did medical therapy. Preoperative BMI and weight loss did not predict the improvement in hyperglycemia after these procedures."

    Dr. Robin Blackstone, president of the American Society of Metabolic and Bariatric Surgery, is hopeful that the evidence of both studies will encourage insurers to extend surgical coverage to diabetic patients sooner than current standards, or even with lower BMI:

    "These ground-breaking studies will have a major impact on the future of diabetes treatment as clinicians, patients, government officials, and insurers absorb the data and its implications. But while bariatric surgery proved more effective than medical therapy for type 2 diabetes, the real winner is patients, who may now gain greater access to a safe and proven treatment that has been denied too long to too many." (See Dr. Blackstone's full statement.)

    The Bariatric and Metabolic Weight Loss Center here at Stony Brook works with our patients to treat diabetes. For more information about our program or to register for a educational seminar, please visit us on the web.

    Follow Dr. Pryor on Twitter!

  • New Heart, More Life: Cheney's VAD "Bridge to Transplant" Success Story

    By Allison J. McLarty, MD, Co-Director, Ventricular Assist Device Program, Stony Brook Heart Institute

    Former Vice President Dick Cheney, age 71, received a heart transplant this past weekend, after spending more than 20 months of being kept alive by a ventricular assist device (VAD) — artificial heart pump — that had been implanted in him to buy him time until he could have the transplant.

    Prior to the VAD implantation, Mr. Cheney had suffered a total of five heart attacks, the first of which was in 1978 when he was 37 years old. After his last heart attack in early 2010, he was treated for advanced heart failure.

    With progression of his heart failure, he was offered the option of VAD "bridge to transplant" therapy to support him while he waited for a heart transplant.

    America watched as the former vice president reclaimed his life following the 2010 implantation of the VAD called HeartMate 2.

    The HeartMate 2 supported Mr. Cheney until an appropriate donor heart became available for his transplant operation. Not only that, during the period he relied on this mechanical heart, he was living a full life out in the world.

    This particular VAD represents a new generation of artificial heart technology that offers patients with end-stage heart failure, like Mr. Cheney, access to an important new treatment option. Approved by the FDA in 2010, it is the only VAD approved for use as a bridge to transplant, as in his case — and also for use as "destination therapy" for those patients ineligible for a heart transplant.

    At Stony Brook we have observed similar dramatic improvement in quality of life in our patients in whom we have implanted the HeartMate 2. Many have returned to work, travel, and participate in a normal lifestyle with little limitation.

    VADs can be used for months if not years to bridge or buy time for patients with heart failure, as they await a donor heart to become available. Often, as in the case of Mr. Cheney, donor hearts that are a "match" are not available for several months to years.

    The HeartMate 2 is a surgically placed device that I implant next to the heart to help its main pumping chamber, the left ventricle, pump blood through the body.

    Stony Brook VAD Certificate | Joint Commission
    Stony Brook's VAD certification
    was granted in March 2011.

    The many months' support of Mr. Cheney on the HeartMate 2 VAD is a testimony to the durability and effectiveness of this life-saving technology.

    Stony Brook Heart Institute's VAD program is the only program of its kind on Long Island to offer this leading-edge treatment of end-stage heart failure.

    Our VAD program has been accredited by the Joint Commission, which further distinguishes it and the quality of care we provide here at Stony Brook.

    We treat three types of advanced cardiac patients with VADs. Patients like Mr. Cheney, in whom the device is used as a temporary support until a heart transplant is arranged, in addition to patients who, because of their age or other concomitant diseases, are not eligible for transplantation but nonetheless have advanced cardiac disease.

    In certain cases, the device has been reported to function in excess of nine years as a form of permanent support, that is, destination therapy. In other but rare cases, the VAD is placed in patients in whom we believe the device will one day be removed after the patient's own heart has recovered its normal function.

    Our team of heart failure cardiologists, surgeons, and nurses follows our patients closely once they leave the hospital. In addition, Stony Brook has spearheaded a concerted outreach effort to educate our colleagues and community on Long Island about the effectiveness of VAD therapy, and to support the growing number of VAD patients and their families who now live here.

    See "Heart Failure Patients Seek 'Cheney Pump'" story on ABC News. Watch this short video (1:20 min) about the HeartMate 2 VAD technology (see how it works):

  • Demand for Cosmetic Surgery among Aging Baby Boomers Is on the Rise

    By Mary Zegers, RN, BSN, CNOR, Patient Care Coordinator, Breast and Reconstructive Plastic Surgery

    Mary Zegers, RN, BSN, CNOR
    Mary Zegers, Patient Care
    Coordinator

    It's beginning to look like plastic surgery is recession proof. Each year the demand for plastic surgery continues to steadily increase, and the greatest requests for cosmetic surgery are coming from baby boomers, people born between 1946 and 1964, who currently represent one quarter of the population of the United States.

    Approximately 79 million baby boomers, it is believed, will live to be 93 years old. And as boomers age, just as they challenged society's expectations when younger, they are questioning what it means to be a senior citizen. Along these lines, "seniors" are now looking to cosmetic surgery as an appealing option for various reasons.

    There is a real ecomomic need to look younger. Due to the financial recession, the downgrade of the mortgage industry and the long-term investment scares, fewer people will be able to retire when they dreamed they could.

    According to a recent study by the Employee Benefit Reasearch Institute, less than 15% of Americans age 50 and older plan to retire by age 70.

    Not only are seniors working a lot longer, they are competing against younger people in a competitive job market. The need to look and act younger for professional reasons is driving an unparalleled interest in cosmetic procedures among Americans 50 and older.

    As Americans live longer and continue to stay active,
    the increased demand for cosmetic procedures will likely continue to grow.

    The journal Plastic and Reconstructive Surgery published a report in 2011 that found patients age 65 years and older did not face any significant greater hazards from face-lift surgery than younger patients (see abstract of report).

    Interestingly enough, more and more men are requesting cosmetic procedures. For example, facelifts for men are up 14% from 2009-2010, according to the American Society of Plastic Surgeons.

    In 2010, aproximately 3.3 million Americans age 55 years and older underwent cosmentic procedures. Of these treatments, 84,685 were surgical procedures:

    • 26,735 facelifts
    • 24,783 eyelid operations
    • 6,469 liposuction procedures
    • 5,874 breast reductions
    • 3,875 forehead lifts
    • 3,339 breast lifts
    • 2,414 breast augmentations
                  Because boomers came of age in a world fascinated by them, and partially created for them, we are often not the most cooperative when it comes to aging. We are, in fact, at the forefront of not just aging gracefully, but not aging at all. Against all odds, we will hold back the hands of time. — Wendy Wasserstein
    As Americans live longer, remain more active, and continue to become more educated about how to stay healthy, there will likely continue to be increased demand for cosmetic procedures.

    People are changing their lives both personally and professionally after the age of 50 years in much greater numbers than in the past. The overall thinking is, Why not look good while doing it?

    Our thinking is that people of any age who want cosmetic surgery should be sure to go to a board-certified plastic surgeon in order to ensure the highest level of both safety and quality outcomes.

    At the Stony Brook Cosmetic & Plastic Surgery Center, our team of plastic surgeons specializes in providing cosmetic surgery for adults of all ages, as well as children with special needs.

  • FAQs about Innovative Minimally Invasive Techniques for ENT-Head and Neck Surgery

    Treating Cancer and Other Disorders with State-of-the-Art Technology

    ENT-head and neck surgeons Ghassan J. Samara, MD, and Mark F. Marzouk, MD, of our Otolaryngology-Head and Neck Surgery Division, discuss two innovative minimally invasive techniques — robot-assisted surgery for ENT procedures and salivary endoscopy — and how they benefit patients with cancer and other disorders.

    Q: What is the role of robot-assisted surgery for ENT procedures?

    A: Although robot-assisted surgery has been used for heart, gastrointestinal, urinary, gynecologic, and other surgeries over the past decade, only recently has it become available for ear, nose, and throat surgery. The high-tech robotic platform employed by Stony Brook is called the da Vinci® S HDTM Surgical System.

    Basically, our robotic system allows us to insert a 3D telescope about one quarter inch in size through the mouth. This gives excellent visibility, access, and magnification of areas that in the past were unreachable with surgical instruments. We can use it to diagnose and treat cancers of the mouth, throat, and tongue, remove tonsils with little or no blood loss, treat sleep apnea, and perform microsurgery in areas that were previously inaccessible.

    Dr. Samara was the first physician on Long Island to use robot-assisted surgery for ENT procedures, performing the first case in the spring of 2011 (read all about it).

    In the past, ENT surgeons needed to cut through the jawbone, lips, or neck to open up the throat, so the new robot-assisted procedure offers a huge advantage to patients in terms of minimizing blood loss, pain, and recovery times. It also gives surgeons an unprecedented perspective — almost as if you were standing inside the throat or mouth itself. The magnification is so great that not only do you see things much clearer, you also see things you never saw before.

    Q: What is salivary endoscopy and what is it used for?

    Dr. Mark Marzouk Performing Salivary Endoscopy
    Dr. Marzouk (left) performing salivary endoscopy
    procedure with the assistance of Dr. Samara;
    note endoscopic view of salivary gland stone
    (arrow; click on photo to enlarge) just under one
    quarter inch, prior to removal from gland duct.

    A: Salivary endoscopy is a minimally invasive technique that allows us to examine the salivary ducts (the place where saliva passes from the salivary gland into the mouth) through an endoscope and make a diagnosis. At the same time, we also can perform treatment; for example, removal of stones from the salivary gland (sialolithiasis), duct dilation and steroid injection, or removal of scar tissue caused from radiation or chemotherapy used in thyroid cancer treatments.

    Dr. Marzouk was the first physician on Long Island to use salivary endoscopy, performing the first case in the fall of 2010 (read all about it).

    This approach is ideal for patients because they do not need multiple procedures, and it can be done on an outpatient basis. Previous treatment involved surgical removal of the entire salivary gland, which entailed an incision in the neck and an overnight hospital stay.

    The new procedure is most frequently used for sialolithiasis — a condition that affects approximately 12 in 1,000 adults. Salivary endoscopy spares the gland without risk to vital structures such as the tongue and facial nerves. Recovery time is also faster than with the previous open surgical technique, and patients may return to a normal diet the same day. Current literature reports the success rate of these procedures at 90%, with a less than 5% recurrence. (Click here to read more about salivary endoscopy.)

    Q: Where are these minimally invasive techniques available?

    A: In Suffolk County, only at Stony Brook University Hospital. The first salivary endoscopy procedure was performed in October 2010, and growing numbers of patients are benefitting from it. As for the robot-assisted surgery, fewer than 100 surgeons worldwide have been trained on the equipment, and there are just a few in New York State. Both of these techniques improve the patient's experience, promoting faster healing and a faster return to normal activities.

    Q: Are there other breakthroughs that can benefit patients with head and neck cancer?

    A: Yes, RapidArc® is a radiotherapy technology that is being used at Stony Brook for patients with head and neck cancer, and it is among the most advanced forms of intensity modulated radiation therapy. RapidArc delivers beams two to eight times faster than conventional radiotherapy, so patients do not have to hold still for long periods of time. This, in turn, makes patients more comfortable and improves the quality of care. There is also less of a chance that patients will shift or move, so the radiation is more highly targeted.

    This precision of delivery means that the radiation goes to where it is needed — the tumor — and not the healthy tissue surrounding it. As a result, patients tend to have less intense side effects associated with treatment.

    Come to our community update on head and neck cancers, to be held at the Stony Brook Cancer Center on Wednesday, May 23! Learn about surgical advances including minimally invasive techniques and reconstructive surgery for cancers of the thyroid, head, and neck. Radiation oncology treatment, speech pathology, and the latest research will also be discussed. A question-and-answer session will follow the presentation. Click here for details — see program announcement.

    Please use our comments feature to submit your own questions to Drs. Marzouk and Samara about the procedures described here (see posted comments at bottom of page).

  • Our Trauma Service Ranks among the Best Statewide, Says Health Department Report

    University Hospital the Second Hospital Ever to Repeat This Achievement in Two Consecutive Reports

    Stony Brook University Hospital is the only designated Level 1 regional tr

    The 1.5 million residents of our region are in the best of hands if they are injured and need emergency care. That's really good news! For the latest report of the New York State Trauma System Program, just issued by the NYS Health Department, Stony Brook University Hospital has demonstrated a lower than expected risk-adjusted mortality rate for the "severe" traumatic injury patients that form the state registry data set.

    This high level of performance makes us one of only four trauma centers statewide to have a statistically significant lower than expected mortality rate, and the second hospital ever in New York to repeat this achievement in two consecutive reports.

    University Hospital — our region's only state-designated Level 1 Trauma Center — is among four of 40 trauma centers in the state with survival rates for patients with severe traumatic injury that are significantly above the statewide average.

    Suffice it to say, this record of achievement makes us all proud of the excellent clinical care that we provide here at Stony Brook University Hospital, and proud of our trauma registry which records such care with accuracy and completeness.

    "This is truly a credit to all the individuals involved in our trauma system, from the physicians from all services and departments, which include attendings, fellows, and residents to the nurses, physical and occupational therapists, care coordinators and social workers, and respiratory therapists, together with the support from Stony Brook Medicine's administration," says Marc J. Shapiro, MD, who served as our chief of trauma/surgical critical care during the period of the state's last two reviews of our trauma care performance.

    Record of Excellence in Trauma Care

    Our trauma service treats more than 1800 patients annually, among whom at least 800 on average have moderate to severe injuries. Those 800 patients per year are the subject of the state's new three-year report on risk-adjusted mortality.

    In addition to direct admissions, we consult on and receive transfers of complex, critically injured patients from all points in Suffolk County, and every community and Level 2 trauma hospital in the region. Stony Brook also serves as EMS control for all of Suffolk County's ground and air ambulances.

    Our trauma service has been recognized by multiple state and federal healthcare agencies as providing among the highest level of care to injured patients in the country.

    According to the Agency for Healthcare Research and Quality, Stony Brook's trauma service is in the top 4% of trauma centers nationwide, with the lowest mortality of any hospital in the United States in treating pedestrian trauma.

    NYS Trauma System Reports are periodically produced by the Health Department as quality management tools to document the efficacy of the NYS trauma system. These reports use NYS trauma registry data to detail risk-adjusted mortality rates by trauma center, level of trauma center (regional vs. area), trauma region, and mechanism of injury.

    Two types of mortality are examined: "in-patient" (only those severely injured patients who died after being admitted to the trauma center hospital) and "in-hospital" (all severely injured patients who died in the hospital — both the "in-patient" and those that died in the emergency department).

    The new NYS trauma report documents that our risk-adjusted survival rate for the study period (2007-2009) was 95.15%, compared to the state observed average of 93.81% during this period. The expected survival rate for Stony Brook's patients was 93.22%, based on patients' level of acute illness or injury.

    Click here to see the executive summary of the new trauma report of the New York State Trauma System Program.

  • New Report Affirms Lifesaving Role of Colonoscopy: Death Risk Is Cut in Half

    By Roberto Bergamaschi, MD, PhD, Chief of Colon and Rectal Surgery

    I read with interest the article just published in The New England Journal of Medicine. In a National Polyp Study, Dr. Ann Zauber and her colleagues determined that colonoscopic polypectomy — that is, the removal of benign colorectal growths called polyps — prevents colorectal cancer deaths.

    This observation and conclusion have been well established, but it is always a good idea to restate the importance of screening and prevention of this potentially highly curable malignancy.

    What has improved are the methods of dealing with larger polyps, those which cannot safely be removed through the colonoscope.

    Classically, a major abdominal operation with bowel resection has been required to remove these larger polyps. The colon and rectal surgery service at Stony Brook offers patients with such difficult polyps a less invasive approach to polyp removal.

    This minimally invasive procedure takes place in the operating room, and involves two physicians working together. One physician watches the outside of the colon via a camera placed through the umbilicus (bellybutton), while the second physician uses a colonoscope to remove the difficult polyp.

    This approach affords the physicians direct visualization of the colon to confirm that the full polyp was removed and that no damage has been done to the outside of the colon.

    The new report, "Colonoscopic Polypectomy and Long-Term Prevention of Colorectal-Cancer Deaths," shows that removing polyps during a screening colonoscopy not only prevents colon cancer from developing, but also prevents deaths from the disease.

    The scientists who conducted the study found that in patients tracked for as long as 20 years, the death rate from colon cancer was cut by 53% in those who had a colonoscopy and whose doctors removed the precancerous growths.

    March is National Colorectal Cancer Awareness Month! Click here to learn more about the observance of this health month, plus find information about colorectal cancer and how to prevent it.

  • FAQs about Vascular Disease in Women: Three Major Conditions to Know

    Diseases of the vascular system can strike suddenly and without warning — often with deadly results. That's why it's best to identify and treat underlying causes before symptoms appear.

    To mark the final days of Women's Heart Health Month this February, Apostolos K. Tassiopoulos, MD, chief of vascular surgery, answers the basic questions about three major vascular conditions that can jeopardize the health of women (and men too).

    Q: How does carotid artery disease affect women?

    A: Carotid artery disease can lead to stroke, which is the number one cause of disability in older Americans. Strokes affect over 425,000 women each year — 55,000 more than men — and occur when blood flow to the brain is obstructed by plaque or a clot, or when pieces of plaque break off and flow to the brain.

    Fortunately, carotid artery disease can be detected before symptoms appear with a duplex ultrasound test, and can be treated with medications in early stages. Plaque in the carotid arteries that produces symptoms or creates significant narrowing is treated with surgery (endarterectomy) or minimally invasive procedures (stents).

    Q: What are abdominal aortic aneurysms (AAAs)?

    A: The aorta is the largest artery, delivering oxygen-rich blood to the entire body. When the wall of the aorta weakens, the pressure makes it bulge to form an aneurysm. Aneurysms can enlarge over time without symptoms and may eventually rupture, causing severe internal bleeding. More than 80% of patients who suffer a rupture die from this condition.

    The good news is that symptomless AAAs can be found through abdominal ultrasound or CT scans, and can be safely observed while treating risk factors in early stages. If the aneurysm exceeds 2.2 inches in diameter, we recommend treatment with minimally invasive endovascular stent grafts or open surgical repair.

    Q: What is peripheral artery disease (PAD)?

    A: PAD is plaque buildup in the leg arteries that can result in leg pain, difficulty walking, non-healing foot sores and, in advanced stages, can lead to amputation. Patients with PAD frequently have plaque buildup in the coronary and carotid arteries, and are at higher risk for heart attack — the number one cause of death in women — and stroke.

    So identifying PAD early is important not only for improving leg health, but for reducing the risk of heart attack and stroke as well. Medications and lifestyle changes are used to treat early PAD. Those with advanced disease and symptoms that pose a threat to the limb are treated with minimally invasive interventions (stents) or open surgery.

    Q: What's new in vascular surgery at Stony Brook?

    A: Our Aortic Center offers specialized expertise for those with complex aortic aneurysms. Advances in minimally invasive techniques have allowed us to safely treat older patients and those with more severe disease. And, in terms of research, we are one of 80 institutions nationwide and the only on Long Island selected to participate in a double-blind clinical trial studying the restoration of blood flow to the legs through injections of bone marrow stem cells.

    See information about our vascular disease screenings. Or, click here for our brochure that explains who will benefit most from screening for the three conditions described in this post.

  • New DVT Guidelines Dispute "Economy Class Syndrome": Prolonged Sitting Is Real Cause

    By Antonios P. Gasparis, MD, of the Stony Brook Vascular Surgery Division

    Deep vein thrombosis (DVT) is a leading cause of death in the world. There are several factors that may increase a person’s risk of developing a life-threatening condition.

    The most common risk factors for DVT include previous DVT, recent surgery, hospitalization, trauma, birth control pills, clotting conditions, prolonged travel time, immobility, and cancer. When exposed to these risk factors, several precautions can be taken to help prevent a DVT.

    For years, travelers’ blood clots have erroneously been nicknamed “economy class syndrome.” In fact, it is not the location of one’s seat on an airplane that increases the risk of DVT, but the prolonged immobility during any form of travel.

    For example, NBC reporter David Bloom died of a blood clot he developed while cramped for hours in an army tank recovery vehicle as he was reporting the news on the Iraq war.

    According to the newly released American College of Chest Physicians Guidelines, flights lasting 8 hours or more carry the highest risk.

    Although some claims have been made that DVT risk is increased by airplane window seats, the truth is, it is not these particular seats that increase the risk of developing DVT, but the inherit limitation that window passengers have in moving around the airplane. Window passengers who use appropriate preventive measures have the same risk as other passengers.

    Most important, any type of travel — not only air travel — that has prolonged immobility carries with it an increased DVT risk.

    Prolonged immobility when traveling increases the risk of DVT because blood in the deep veins becomes sluggish, pools, and is more prone to form a clot. Therefore, during long travel it is important to decrease this risk by taking a few simple steps:

    • Doing frequent leg exercises
    • Walking in the aisle
    • Staying well hydrated
    • Using prescribed compression stockings (higher risk people)

    All these steps increase the calf pressure, which helps expel venous blood out of the leg.

    For more information about DVT and how to prevent it, visit the Centers for Disease Control and Prevention.

  • Fixing Broken Hearts with Our Robot: Advancing Minimally Invasive Bypass Surgery

    American Heart Month is the time to address the full range of matters of the heart. The mechanics of it are our specialty, and we fix broken hearts every day. The fact is, more than half a million coronary bypass operations are performed each year in the United States to fix clogged arteries and improve blood flow to the heart.

    At Stony Brook, we use the approach that's best for each individual patient. Many patients are now benefiting from our use of the da Vinci surgical robot to perform what is leading-edge minimally invasive bypass surgery.

    Traditional "open heart" coronary bypass surgery involves stopping the heart to perform the procedure and using cardiopulmonary bypass (CPB); that is, routing the blood through the heart-lung machine to maintain the patient while the heart is stopped. It also requires a large incision and splitting the sternum (breastbone), resulting in a large scar and a lengthy recovery time.

    The mid-1990s saw the advent of the minimally invasive approach to coronary revascularization called "beating heart" surgery, also known as "off pump" surgery. This new approach avoids the use of the heart-lung machine. Consequently, patients do not experience the inflammatory response caused by CPB, which disrupts the body's physiologic balance.

    The minimally invasive direct coronary artery bypass (MIDCAB) beating heart procedure was developed at that time, in addition to other off pump procedures.

    The surgeon performs the operation using the robot — not the other way around.

    Patients needing bypass procedures involving one or two vessel grafts could undergo MIDCAB instead of traditional bypass surgery. Using smaller incisions and not requiring the sternum to be split open, MIDCAB produces less trauma, less pain, and faster recovery.

    Our cardiac surgery service is a national leader in performing robotically-assisted MIDCAB, which constitutes an improvement over the original MIDCAB that requires a five-inch incision and spreading the ribs for access to the heart.

    The new robotically-assisted procedure enables the surgeon to optimize the preparation of the internal mammary arteries, the best vessels for bypass grafts, which produce the most reliable, most protective, and longest-lasting (>20 years) grafts.


    Robotically-assisted MIDCAB offers eligible patients a number of potential benefits over traditional "open heart" bypass surgery:

    • Avoidance of heart-lung machine
    • Best possible quality of bypass grafts
    • Smaller incisions
    • Less pain and scarring
    • Less risk of infection
    • Less anesthesia
    • Less blood loss and fewer transfusions
    • Shorter hospital stay
    • Faster recovery
    • Quicker return to normal activities


    Stony Brook's robot is a highly sophisticated tool that enables surgeons to perform a variety of complex operations, such as coronary bypass surgery. The robotic system makes it possible for them to perform surgery without large incisions by way of superior visualization, enhanced dexterity, and greater precision, which ultimately raises the quality of surgical care.

    Human Hand Compared to da Vinci Endowrist
    Hand of da Vinci robot
    (below) showing its
    greater dexterity com-
    pared to human hand.

    At Stony Brook, Frank C. Seifert, MD, director of minimally invasive bypass surgery, is leading our use of the da Vinci robot to perform MIDCAB surgery. He was specially trained and certified to operate with the robot.

    A nationally recognized expert in MIDCAB and other off pump techniques that avoid the heart-lung machine, Dr. Seifert has performed hundreds of MIDCAB operations at Stony Brook, in addition to more than 2,000 other kinds of beating heart bypass operations. He is one of the few surgeons in the country who mastered the technical challenges of the MIDCAB procedure that have limited its use in the hands of other surgeons.

    Commenting on the significance of the da Vinci surgical robot, Dr. Seifert says: "The robot represents a major advance in coronary bypass surgery that offers patients more benefits of the minimally invasive approach. My operating vision is two to three times greater with it, and there is no loss of depth perception. As visual clues replace touch, the dexterity of the robot's hands is certainly greater than that of the human hand, and should contribute to improved outcomes."

    "Ultimately, with anticipated further advances," emphasizes Dr. Seifert, "robotically-assisted surgery represents the future of all coronary bypass surgery — single or multi-vessel off pump surgery that doesn't require use of the heart-lung machine or the sternotomy incision. "In fact, techniques using the robot are being developed to join the grafted vessels to the heart without use of direct suturing by hand, and then we will see true 'robotic' surgery."

    Click here to learn more about robotically-assisted bypass surgery at Stony Brook.

  • Minnesota Man with Pancreatic Cancer Has Renewed Hope after Surgery at Stony Brook

    Dr. Kevin T. Watkins Performs Procedure to Remove Tumor Previously Deemed Inoperable

    Post-Op with Patient Marc Breton and His Wife Teri, with Dr. Kevin T. Watkins
    Marc Breton, the hopeful patient, with wife Teri
    and Dr. Kevin T. Watkins, following his surgery
    at Stony Brook earlier this month.
    The picture of good health — that is how Teri Breton, wife of Marc Breton, 53, of St. Paul, Minn., describes her husband of 10 years. All that changed on September 29, 2011, when doctors in Minnesota told him about a tumor they discovered in his pancreas via a CT scan. Marc had lost a significant amount of weight only a few short weeks before that time and had become jaundiced.

    During the next two months, Marc's options seemed very limited. Surgeons in Minnesota determined that the tumor was inoperable, mainly because it was wrapped around a major artery and vein. He underwent chemotherapy, which did not appear to shrink the tumor to any significant degree, and he experienced other complications, such as a large abscess on his liver.

    As a program manager for ISEEK.org, a Minnesota career, education, and job resource, Marc is savvy on the computer. He and his family members searched frantically for newer and innovative pancreatic cancer treatment options.

    In their search, they discovered that our renowned surgical oncologist, Kevin T. Watkins, MD, chief of upper gastrointestinal and general oncologic surgery, is a pioneer using irreversible electroporation (IRE), a technique that selectively kills cancer by using electrical fields to generate pores in tumor cells, to remove pancreatic tumors.

    Today, the patient is coming back to Stony Brook for his first follow-up visit with Dr. Watkins — with renewed hope.

    Dr. Watkins was the first surgeon in the world to use IRE technology to treat pancreatic cancer. In the past two years he has treated more than 20 patients with pancreatic cancer at Stony Brook University Hospital with IRE, some who traveled thousands of miles to Stony Brook for the surgery. The treatment is a last-hope option for patients who have run out of other options, and whose cancer has not spread to other areas of the body.

    IRE kills tumor cells without causing collateral damage to adjacent tissue.
    The IRE procedure kills tumor cells without
    causing collateral damage to adjacent tissue.

    Marc, a non-smoker and father of two, approached his oncologist, Steven E. McCormack, MD, about the IRE procedure and Dr. Watkins. Dr. McCormack agreed that IRE may be his best chance for extended survival and quality of life with pancreatic cancer. After a consult with Dr. Watkins, Marc was scheduled for surgery on January 11 of this year.

    To remove the entire tumor, Dr. Watkins used a combination of surgical methods — the standard open Whipple procedure to excise cancerous tissue on the pancreas and remove parts of surrounding organs, which are then reattached; and the IRE procedure for the tumor surrounding the vessels.

    "To incorporate both surgical methods is unusual, and this approach enabled me to obtain a complete resection of Marc's tumor," says Dr. Watkins.

    On January 18, Marc's pathology reports indicated that not only were the tumor margins negative but all of his lymph node tissue was negative for cancer — results which Dr. Watkins refers to as "a best case scenario." Before surgery Marc's chance of beating pancreatic cancer was virtually zero, but now, according to Dr. Watkins, it is about 25%.

    "At the time my tumor was detected my prognosis was grim," says Marc. "But now my prospects for longer-term survival appear much better, and I have a lot more hope."

    Marc recovered quickly from his surgery and went home. He is back on Long Island now, and today he is returning to Stony Brook University Hospital for his first follow-up visit with Dr. Watkins.

    P.S. Dr. Watkins answers FAQs about pancreatic cancer and its treatment. Watch this short video (1:58 min) to see the news-making story about Dr. Watkins helping Marc Breton reported later in the day on WLNY TV 10/55 News (courtesy of TV 10/55):

  • Hope for Patients with Advanced Abdominal Cancers: Increased Survival Time with HIPEC

    The HIPEC Procedure | HIPEC Offers Patients Hope
    The HIPEC procedure is a warm chemo bath
    (click on image to enlarge and animate).

    Stony Brook University Hospital is the only hospital on Long Island to provide HIPEC — heated intra-peritoneal chemotherapy — for the treatment of advanced colon cancer and other late-stage abdominal cancers. In selected patients, HIPEC may increase survival time significantly. It offers patients hope when hope is needed most.

    The HIPEC procedure is an aggressive combination of surgery and chemotherapy to eliminate abdominal tumors. HIPEC, which is performed in the operating room, is designed to kill any remaining cancer cells after all visible tumors are removed.

    The heat improves drug absorption and treatment effect with minimal exposure to the rest of the body. By putting chemotherapy directly into the abdomen, the drug comes into direct contact with the tumor cells.

    Two of our surgical oncologists, Colette R.J. Pameijer, MD, and Philip Q. Bao, MD, provide HIPEC at Stony Brook University Hospital, and they emphasize its survival benefits.

    How: HIPEC involves the use of conventional chemotherapy drugs heated to a high temperature that helps to kill cancer cells. By bathing the abdomen with heated chemotherapy immediately following surgery, a higher dose of medication can be used than would normally be tolerated intravenously.

    Where: The procedure is done in the operating room under general anesthesia. A thorough exploration is done followed by the removal of all visualized tumor. This is followed by the perfusion of heated chemotherapy for up to 2 hours. The entire procedure takes anywhere from 4-10 hours, depending on how much disease the person has.

    Length of hospitalization: About 1 week.

    Benefits: Increased survival time, up to 60% or more in some cases.

    Dr. Pameijer, who established the HIPEC program at Stony Brook four years ago, says: "Patients with carcinomatosis from colorectal cancer may survive 2 years with this treatment, with a good quality of life. While newer systemic chemotherapy agents have improved survival for patients with colon cancer, tumors with this pattern of spread often don’t respond much to systemic chemotherapy. Patients with appendiceal carcinoma or mesothelioma have a 5-year survival rate of as high as 60% with HIPEC."

    3 FAQs about HIPEC

    Q: What are the benefits of HIPEC?

    A: HIPEC allows for higher concentrations of chemotherapy to be delivered into the abdomen and may be more effective than standard intravenous chemotherapy for some tumors.

    HIPEC is the type of treatment that's best at killing microscopic cancer cells (too small to be seen with the naked eye).

    HIPEC in combination with surgery may be more beneficial than standard chemotherapy alone.

    Q: Who is a candidate for HIPEC?

    A: A thorough evaluation is required by our team of experts to determine if a patient is a good candidate for HIPEC. In addition to the presence of stage 4 abdominal cancer, other factors are considered, including the presence of other existing medical conditions, the type and location of the cancer, the surgical history of the patient, and the patient's overall strength.

    Q: What conditions are treatable with HIPEC?

    A: The listed conditions have been found to respond favorably to treatment with HIPEC:

    • Appendiceal cancer
    • Colon cancer with spread to the peritoneum
    • Mesothelioma
    • Ovarian cancer with spread to the peritoneum
    • Primary peritoneal cancer
    • Pseudomyxoma peritonei

    The Appendix Cancer Connection, a non-profit organization devoted to helping patients with appendix cancer and peritoneal surface malignancies, provides information about HIPEC. Another good website is HIPECDoctor.com.

    For more information about our HIPEC program, please call 631-444-8315. Watch this 2011 video (0:51 min) in which Dr. Pameijer describes the program:

  • A New Era in Cardiac Surgery: Valve Surgery without the Surgery!

    By Todd K. Rosengart, MD, Chairman of Surgery and Chief of Cardiothoracic Surgery

    The FDA approval this week of the Edwards SAPIEN aortic valve, which can be passed "over a wire" into the heart without major “open heart" surgery, represents a breathtaking advance in the way heart surgery is performed. Click here to read the FDA's announcement.

    Many of us cardiac surgeons were convinced as recently as three or four years ago that the valve would never work. But it does!

    It is likely that tens of thousands of patients at increased risk for valve surgery — the indication for which the FDA approved the device — will be candidates for this procedure in the U.S. It is already widely used in Europe, where it was approved several years ago.

    The "percutaneous" SAPIEN valve, placed into position to replace narrowed, or "stenotic" aortic valves, will be available for high-risk patients with severe aortic stenosis. There are about 300,000 such individuals in the U.S. alone.

    The valve is placed during a procedure called TAVI, the acronym for transcatheter aortic valve implantation. Results in a major U.S. trial of this device, the PARTNER trial, showed about twice as good survival after procedures for high-risk patients with the TAVI approach as compared to standard surgery.

    On the other hand, the risk of stroke was about twice as high in the TAVI group than in the group of patients who underwent standard surgery — a result that is expected to improve as experience with the procedure grows and device design improves.

    TAVI is here, and joins an increasingly "minimally invasive" environment for open heart surgery.

    The present stroke risk is the reason that the FDA is approving the device only for use in treating patients who are at high risk for the standard surgery, which puts relatively greater stress on their bodies.

    So, TAVI is not without significant risks despite the fact it allows doctors to avoid major open surgical implantation procedures.

    Edwards SAPIEN aortic valve
    Edwards SAPIEN aortic valve (click on
    image to enlarge)

    Likewise, there is no "track record" on how long the Sapien device will last once implanted, and this is another reason it will not be available to replace all standard aortic valve replacements.

    TAVI joins an increasingly "minimally invasive" environment for open heart surgery, potentially offering patients the several benefits of this approach.

    At the Stony Brook Valve Center, for example, most valve operations are now performed through small incisions between the ribs (“mini-thoracotomy") without opening the breastbone as in standard surgery.

    As with TAVI, we have found this minimally invasive approach to be safer for our patients than conventional open surgery.

    The world of surgery is quickly changing. More to come!Follow Dr. Rosengart on Twitter!